COVID-19 Treatment Options?

There was no benefit observed with lopinavir–ritonavir treatment compared to standard care hospitalized adult subjects with severe Covid-19, which was based on the study “A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19".

Most awaiting results of Ebola targeted “Remdesivir” yet to be published. Based on previous trials which showed high potency against RNA viruses.

Anti-Malarial drug “Chloroquine” showing significant efficacy so far against covid19.

Seasonality will effect many viruses and viruses replicate more at temperatures less than 37°C in general. I assume that keeping high temperatures may suppress the growth and transmission of novel Corona virus(2019-nCoV). Based on the previous literature, cell viability and viral replication were reduced the A/H1N1 2009 virus at 37 °C and 40 °C.

There no antiviral treatment established for COVID-19 infection till date. Anti-virals like lopinavir/ritonavir, remdesivir/chloroquine, favipiravir and ribavirin may be the potential drugs for COVID-19 .
Based on previous literature's, these drugs were effective and showed favorable clinical response.

Quick Links:
1. 2019NovelCoronavirus,Prevention&Treatment(CDC)
2. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
3. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro
4. Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
5. Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings
6. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)
7. Novel coronavirus (COVID-19) situation as of 13 February 2020, 10:00 (CET)

8. https://www.nature.com/articles/d41587-020-00003-1